涓闄㈡槅鏄庡姩鐗╃爺絀舵墍瀵煎笀浠嬬粛:鏇規(guī)瘏_璺ㄨ€冪綉
銆€銆€鏇規(guī)瘏錛?a target="_blank">涓浗縐戝闄?/a>鏄嗘槑鍔ㄧ墿鎵€鐮旂┒鍛?/p>
銆€銆€姣曚笟浜?a target="_blank">鍥涘窛澶у鍗庤タ鍖誨闄㈠尰瀛︿笓涓氥€?寰峰浗鏌忔灄媧牎澶у鍗氬+銆傚痙鍥芥搗寰峰牎寰峰浗鐧岀棁鐮旂┒涓績(jī)鍗氬+鍚庛€備粠浜嬩復(fù)搴婄梾鐞嗚瘖鏂紝鐢熺墿鍖誨鍩虹鍙?qiáng)鋸?fù)搴婄爺絀朵簩鍗佷綑騫淬€傚湪涓婃搗鍚屾祹澶у鍖誨闄㈢梾鐞嗘暀鐮斿宸ヤ綔涓冨勾錛屽痙鍥界爺絀舵満鏋勶紙鏌忔灄椹厠鎬?榪礉鍏嬪垎瀛愬尰瀛︿腑蹇?jī)銆佹搗寰峰牎寰峰浗鐧岀棁鐮旂┒涓績(jī)銆佸▉灝?dāng)鑼ㄥ牎澶у锛?jí) 鍜屽痙鍥界敓鐗╁叕鍙稿伐浣滃崄鍥涘勾錛屾湡闂村煿鍏繪寚瀵煎崥澹爺絀剁敓澶氬悕銆傚湪鍥介檯瀛︽湳涔﹀垔鍙戣〃鍘熷垱璁烘枃浜屽崄浣欑瘒錛岀敵璇鋒媧?寰峰浗鍙戞槑涓撳埄浜岄」錛屽彈閭€(gè)涓哄瀹跺浗闄呮潅蹇楁挵鍐欑患榪般€傚彈鑱樹(shù)負(fù)涓夊嬈ф床鐢熺墿鍏徃鍚堜綔浼欎即鍜岄【闂€?006騫撮€氳繃涓闄⑩€滅櫨浜鴻鍒掆€濇嫑鑱樿嚦涓浗縐戝闄㈡槅鏄庡姩鐗╃爺絀舵墍錛屼換瀛︾甯﹀ご浜猴紝緇勫緩鍒嗗瓙鐥呯悊瀛﹀疄楠屽銆?/p>
銆€銆€涓昏瀛︽湳鎴愮嘩錛?/p>
銆€銆€鍒嗗瓙鐥呯悊瀛︽槸搴旂敤鍒嗗瓙鐢熺墿瀛︽柟娉曪紝鍦ㄥ垎瀛愭按騫崇爺絀剁柧鐥呯殑鍙戠敓銆佸彂灞曘€佹満鐞嗭紝涓轟復(fù)搴婅瘖鏂€佹不鐤椼€侀闃叉湇鍔°€備腑鍥界瀛﹂櫌鏄嗘槑鍔ㄧ墿鎵€鍒嗗瓙鐥呯悊瀛﹀疄楠屽鏄柊鎴愮珛鐨勫縐戠粍錛屼富瑕佷粠浜嬩簬鑲跨槫鍒嗗瓙鐥呯悊錛屽厤鐤梾鐞嗙殑鍩虹鍙?qiáng)鋸?fù)搴婄爺絀躲€傜洰鐨勬槸寤虹珛鑲跨槫鏃╂湡璇婃柇錛岀敓鐗╂不鐤楃殑鏂版柟娉曘€傚湪榪囧幓鐨勫伐浣滀腑錛屾垜浠凡寮€鍙戝嚑鏍€傜敤鍨嬭偪鐦よ瘖鏂€у崟鍏嬮殕鎶椾綋錛岃幏寰椾笓鍒╋紝騫跺凡鍋氭妧鏈漿璁╁拰榪涘叆涓村簥搴旂敤銆備富瑕佸熀浜庢垜浠殑鍗曞厠闅嗘姉浣擄紝鎴戜滑宸插緩绔?涓柊鐨凜D marker錛屽茍鐮旂┒鍏跺姛鑳藉強(qiáng)涓村簥鎰忎箟銆傞嬈$粨鍚堥珮鏁廝CR鏂規(guī)硶鍙?qiáng)鐗瑰紓鐨?a target="_blank">鍏嶇柅瀛?/a>鏂規(guī)硶寤虹珛鍘熶綅鍏嶇柅PCR鏂規(guī)硶錛屾涓哄艦鎬佸鎶€鏈柟娉曠殑閲嶈榪涙銆傚緩绔嬮浮鍗佃泲鐧斤紙Ovalbumin錛変腑鏋㈢緇忚漿鍩哄洜灝忛紶錛屽茍鍩轟簬姝よ漿鍩哄洜灝忛紶寤虹珛鍑犱釜瀹為獙鎬ц嚜韜厤鐤€ц剳鑴婇珦鐐?錛圗AE錛?鍔ㄧ墿妯″瀷銆傚叾涓€鏄涓€鏍嚜鍙戞€D8緇嗚優(yōu)璇卞鐨凟AE鍔ㄧ墿妯″瀷銆傚叾緇撴灉鍙兘瀵瑰鍙戞€х‖鍖栫殑鐮旂┒錛?璇婃柇錛?娌葷枟甯︽潵閲嶅ぇ褰卞搷鍙?qiáng)鏀瑰彉銆?/p>
銆€銆€閫夋嫨璁烘枃錛?/p>
銆€銆€1. Cao Y錛?Toben C錛?Na SY錛?Stark K錛?Nitschke L錛?Peterson A錛?Gold R錛?Schimpl A錛?H眉nig T. Induction of experimental antoimmune encephalomyelitis in transgenic mice expressing ovalbumin in oligodendrocytes. European Journal of Immunology錛?6錛?07錛?2006.
銆€銆€2. Goletz S錛?Cao Y錛?Danielcyk A錛?Ravn P錛?Schoeber U錛?Karsten U. 2003. Thomsen-Friedenreich antigen錛?the 鈥瞙idden鈥?tumour antigen. Advances in Experimental Medicine and Biology錛?535 錛?147-162.
銆€銆€3. Cao Y錛?Merling A錛?Crocker PR錛?Schwartz-Albiez R. 2002. Differential Expression of b-galactoside a2錛? sialyltransferase 錛圫T6Gal.I錛?and sialoglycans in normal and cirrhotic liver and hepatocellular carcinomas. Laboratory Investigation錛?82錛?515-1524.
銆€銆€4. Cao Y錛?Merling A錛?Karsten U錛?Schwartz-Albiez R. 2001. The fucosylated histo-blood group antigens H type 2 錛坆lood group O錛?CD173錛?and Lewis Y 錛圕D174錛?are expressed on CD34 hematopoietic progenitors but absent on mature lymphocytes. Glycobiology錛?11錛?77-683.
銆€銆€5. Cao Y錛?Kopplow K錛?Liu G-Y. 2000.In-situ immuno-PCR to detect antigens. The Lancet錛?356錛?002-1003.
銆€銆€6. Cao Y錛?Karsten U錛?Otto G錛?Bannasch P. 1999. Expression of MUC1錛?Thomsen-Friedenreich antigen錛?Tn錛?sialosyl-Tn錛?and 偽2錛?-linked sialic acid in hepatocellular carcinomas and preneoplastic hepatocellular lesions. Virchows Archiv錛?434錛?03-509.
銆€銆€13. Cao Y錛?Karsten U錛?Hilgers J. 1998. TD-4 Workshop 錛圙roup #9錛夛細(xì) Immunohistochemical characterization of a panel of 56 antobodies with normal human small intestine錛?colon錛?and breast tissues. Tumor Biology錛?19錛坰uppl 1錛夛細(xì)88-99.
銆€銆€14. Cao Y錛?Blohm D錛?Ghadimi BM錛?Stosiek P錛?Xing P-X錛?Karsten U. 1997. Mucins 錛圡UC1 and MUC3錛?of gastrointestinal and breast epithelia reveal different and heterogenous tumor-associated aberrations in glycosylation. The Journal of Histochemistry & Cytochemistry錛?45錛?547-1557.
銆€銆€16. Cao Y錛?Stosiek P錛?Springer GF錛?Karsten U. 1996. Thomsen-Friedenreich-related carbohydrate antigens in normal adult human tissues錛?A systematic and comparative study. Histochemistry and Cell Biology錛?106錛?97-207.
銆€銆€17. Cao Y錛?Karsten U錛?Liebrich W錛?Haensch W錛?Springer GF錛?Schlag P. 1995. Expression of Thomsen-Friedenreich-related antigens in primary and metastatic colorectal carcinomas錛?A re-evaluation. Cancer錛?76錛?700-1708.
銆€銆€涓撳埄錛?/p>
銆€銆€1. Karsten U錛?Cao Y錛?Haase M錛?Kiefer M. Monoklonale Antik rper gegen epitheliales Muzin 錛圡UC1錛夈€?DE19534630 A1 錛?8.09.1995錛夈€?/p>
銆€銆€2. Karsten U錛?Cao Y錛?Butschak G錛?Haase M錛?Kiefer M. Monoklonale Antik rper gegen das Thomsen-Friedenreich-Antigen錛?ihre Herstellung und ihre Verwendung zum Tumornachweis. DE 4329004A1 錛?8.08.1993錛夈€?/p>
銆€銆€鑱旂郴淇℃伅錛?/p>
銆€銆€鐢?shù)璇濆Q?871-5199081錛堝姙錛?/p>
銆€銆€Email錛歝aoy@mail.kiz.ac.cn
銆€銆€鍦板潃錛氭槅鏄庡競(jìng)鏁欏満涓滆礬32鍙蜂腑鍥界瀛﹂櫌鏄嗘槑鍔ㄧ墿鐮旂┒鎵€
銆€銆€閭紪錛?50223
?涓闄㈡槅鏄庡姩鐗╃爺絀舵墍
銆€銆€2022鑰冪爺鍒濆璇曞凡緇忔帴榪戝熬澹幫紝鑰冪爺瀛﹀瓙鍏ㄩ潰榪涘叆2023灞婂鑰?/b>錛岃法鑰冧負(fù)23鑰冪爺鐨勮€冪敓鍑嗗浜?0澶ц鍖呭叏紼嬪噯澶囥€佸叏騫村涔?fàn)澶囪€冭鍒掋€佺洰鏍囬櫌鏍′笓涓氳緟瀵箋€佸叏鐪熷璇曟ā鎷熺粌涔?fàn)鍜屽叏绋嬮拡瀵规€ф寚瀵鹼紱2023鑰冪爺鐨勫皬浼欎即閽堜篃宸茬粡寮€濮嬫嫨鏍″拰澶嶄範(fàn)浜?jiǎn)锛岃法鑰冭€冪爺鐣呭5.0鐗堟湰鍏ㄦ柊鍗囩駭錛屾棤璁轟綘鍦ㄦ牎鍦ㄥ閮藉彲浠ユ洿鑷鐨勫畬鎴愪綘鐨勮€冪爺澶嶄範(fàn)錛?/a>鏆戝亣闆嗚钀?/span>甯︽潵浜?jiǎn)闄㈡牎涓撲笟鍒濇閫夋嫨錛屾槑紜柟鍚戯紱鑰冪爺澶囪€冨叏騫磋鍒掞紝鏍稿績(jī)鐭ヨ瘑鐐瑰叆闂紱涓€у寲鍒跺畾澶囪€冩柟妗堬紝鍔╀綘璧㈠湪璧瘋窇綰匡紝鏃╁嚭鍙戜竴鐐圭鎴愬姛灝辨洿榪戜竴鐐癸紒
鐐瑰嚮鍙充晶鍜ㄨ鎴?/strong>鐩存帴鍓嶅線浜?jiǎn)瑙f洿澶?/strong>
鑰冪爺闄㈡牎涓撲笟閫夋嫨鍜岃€冪爺澶嶄範(fàn)璁″垝 | |||
2023澶囪€冨涔?/td> | 2023綰夸笂綰夸笅闅忔椂瀛︿範(fàn) | 34鎵€鑷垝綰塊櫌鏍¤€冪爺澶嶈瘯鍒嗘暟綰挎眹鎬?/td> | |
2022鑰冪爺澶嶈瘯鏈€鍏ㄤ俊鎭暣鐞?/a> | 鍏ㄥ浗鍚勬嫑鐢熼櫌鏍¤€冪爺澶嶈瘯鍒嗘暟綰挎眹鎬?/a> | ||
2023鍏ㄦ棩鍒跺皝闂緇?/span> | 鍏ㄥ浗鍚勬嫑鐢熼櫌鏍¤€冪爺璋冨墏淇℃伅姹囨€?/a> | ||
2023鑰冪爺鍏堢煡 | 鑰冪爺鑰冭瘯縐戠洰鏈夊摢浜涳紵 | 濡備綍姝g‘鐪嬪緟鑰冪爺鍒嗘暟綰匡紵 | |
涓嶅悓闄㈡牎鐩稿悓涓撲笟濡備綍閫夋嫨鏇撮€傚悎鑷繁鐨?/a> | 浠庡氨涓氳鑰冪爺濡備綍鎷╀笓涓氾紵 | ||
鎵嬫妸鎵嬫暀浣犲浣曢€変笓涓氾紵 | 楂樻牎鐮旂┒鐢熸暀鑲插悇瀛︾闂ㄧ被鎺掕姒?/a> |
鐩稿叧鎺ㄨ崘
璺ㄨ€冭€冪爺璇劇▼
鐝瀷 | 瀹氬悜鐝瀷 | 寮€鐝椂闂?/td> | 楂樺畾鐝?/td> | 鏍囧噯鐝?/td> | 璇劇▼浠嬬粛 | 鍜ㄨ |
縐嬪闆嗚 | 鍐插埡鐝?/td> | 9.10-12.20 | 168000 | 24800璧?/td> | 灝忕彮闈㈡巿+涓撲笟璇?瀵?+涓撲笟璇懼畾鍚戣緟瀵?鍗忚鍔犲己璇劇▼(楂樺畾鐝?+涓撳睘瑙勫垝絳旂枒(楂樺畾鐝?+綺劇粏鍖栫瓟鐤?澶嶈瘯璧勬簮(楂樺畾鐝?+澶嶈瘯璇懼寘(楂樺畾鐝?+澶嶈瘯鎸囧(楂樺畾鐝?+澶嶈瘯鐝富浠?v1鏈嶅姟(楂樺畾鐝?+澶嶈瘯闈㈡巿瀵嗚(楂樺畾鐝?+澶嶈瘯1v1(楂樺畾鐝? | |
2023闆嗚鐣呭 | 闈炲畾鍚戯紙鏀胯嫳鐝?鏁版斂鑻辯彮錛?/td> | 姣忔湀20鏃?/td> | 22800璧?鍗忚鐝? | 13800璧?/td> | 鍏堣闃跺湪綰胯紼?鍩虹闃跺湪綰胯紼?寮哄寲闃跺湪綰胯紼?鐪熼闃跺湪綰胯紼?鍐插埡闃跺湪綰胯紼?涓撲笟璇鵑拡瀵規(guī)€т竴瀵逛竴璇劇▼+鐝富浠誨叏紼嬬潱瀛︽湇鍔?鍏ㄧ▼瑙勫垝浣撶郴+鍏ㄧ▼嫻嬭瘯浣撶郴+鍏ㄧ▼綺劇粏鍖栫瓟鐤?鎷╂牎鎷╀笓涓氳兘鍔涘畾浣嶄綋緋?鍏ㄥ勾鍏抽敭鐜妭鎸囧浣撶郴+鍒濊瘯鍔犲己璇?鍒濊瘯涓撳睘鏈嶅姟+澶嶈瘯鍏ㄧ鏍囧噯鐝湇鍔?/td> |